I would not be surprised if at the very least certain issues will start seeing increasing demand and value, based on what's happened with magazines like Sports Illustrated. Until fairly recently, there was very little interest in SI. But with the popularity of CGC certification (they are the only 3rd party grader currently certifying magazines), values have gone up dramatically.
Look for issues with cultural relevance or crossover appeal. For example, issues of Family Circle with Norma Jean and Batman are in high demand.